it is possible to backup exchange only?

[liorme]

is it possible to backup only exchange items? without the entire vm?

[Gostev]

Yes, however not using Veeam Backup & Replication.
Veeam Backup for Microsoft Office 365 can do it.

[liorme]

meaning i can use the veeam for office 365 to backup an on premise exchange server?

[Polina]

Hi lior,

Yes, that's correct; you can use it to back up on-premises Exchange data. It's also possible to protect hybrid Exchange organizations. Please check out the documentation for more details.