Current setup is as follows:
2 x VMWare ESXi 5.5 hosts in a HA cluster. 7 VMs
1 x Physical HP ML350p w/ Windows Server 2008 R2 & VEEAM 9.5 installed
1 x QNAP TS-653A Backup Target
HP Core switching
Support ID 00547589
QNAP is iSCSI attached to ML350p via a single 1GB NIC currently. When running backup or backup copy jobs we are seeing intermittent throughput between the server and the NAS as per below pic.

VEEAM is reporting the souce is the bottleneck but the QNAP is also reporting very low load.

I have applied the autotuning tweak to the server with no change in performance. Switches are not reporting any issues, and have other services and the VMWare cluster which have no issues. No workstations are reporting speed issues, and I can generally copy data to and from the NAS at a good speed from within the Windows server (and without the drops of transfer rate).

I would be happy with slow but constant performance, as I'm not expecting the world but the constant drops to 0KB speed are making life extremely difficult.
Can anyone point me in the right direction?