You probably need the hotfix. It's a Microsoft hotfix for .Net applications that handle large XML files....exactly what our Collector is
It will work when using both v4 and v5 nworks.
Without the hotfix you can see very high Handle Count for Ops Mgr agent processes (Health Service, Monitoring Host). This causes the Ops Mgr agent to auto-restart itself.
You can also override Handle Count threshold rules in Ops Mgr, but to get best system stability and a permanent fix I recommend the hotfix.
let me know how it goes!