Just don't expect to be backing them up to tape. Even though 9.5 finally made it possible to avoid having tape copy jobs terminate when the primary backup job starts, I don't think Veeam is capable of parallel tape drive usage when copying a single VM even in 9.5. We backup multiple 10TB+ VM's daily, but a single LTO6 drive takes days to copy a full backup of just one of them.
It's extraordinarily aggravating.
Also, Seve CH, you're adorable.
It's "stun time", btw. It's a shame that with the huge head start VMware had that they could not implement a ReFS 3.0/NetApp/Everybody but VMware style snapshot system before Microsoft. We still have to consider snapshot deletes a potentially disruptive event.