thanks for the question.
For Veeam it do not matter if the the WAN Accelerator and Proxy Server run on same server or not. The needed resources are the same.
You can check the Best practices guide https://bp.veeam.expert/
for the actual WAN accelerator tuning recommendations.
Sometimes it is faster for high frequent replications to not use the WAN accelerators. I suggest you test with and without. High frequent replications lead into small change rate and default compression is maybe enough to process the data through the WAN link. WAN accelerators are only helpful if the WAN links is saturated and the extra time an WAN accelerator need for the extra processing lead into faster overall processing.
In the best practices guide you will find a lot of tips and tricks for Replication optimization.
Let me just add that you have a huge job count for your number of VMs. Typically there are on average more than 20 VMs in a Job.